ea0032p857 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013
Coculescu Mihail
, Campean Anca
, Stancu Cristina
, Capatina Cristina
, Livia Gheorghiu Monica
, Caragheorgheopol Andra
, Hortopan Dan
, Ciubotaru Vasile
, Raica Marius
Introduction: SOX2 is an early developmental transcription factor and a marker for pituitary progenitor cells.The study aimed to investigate if the pituitary adenomas with positive SOX2 immunoreactivity shows a different response to therapy as compared with controls.Patients and methods: We investigated 15 pituitary macroadenomas, eight with SOX2 immunoreactivity (SOX2+) and seven without (SOX2−) (controls); five were GH prod...